Mast Cell
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Mast cell - A mast cell (or mastocyte) is a resident cell of connective tissue that contains many granules rich in histamine and heparin. Although best known for their role in allergy and anaphylaxis, mast cells play an important protective role as well, being intimately involved in wound healing and defense against pathogens.
Mast cell disease - Mast cell diseases comprise a heterogeneous spectrum of diseases involving the mast cells. The most common variants are:
Mastocytoma - A Mastocytoma is an accumulation or nodule of mast cells that resembles a tumor. In dogs and cats this collection of mast cells is actually a mast cell tumor.
Tryptase - Tryptase is the most abundant secretory granule-derived serine proteinase contained in mast cells that has recently been used as a marker for mast cell activation. It is involved with allergenic response and is suspected to act as a mitogen for fibroblast lines.
mastcell
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